HIGHLIGHTS
- who: Yuxuan Zhen from the , lpr/Axl-KO mice were generated by crossingmice (Jackson Laboratory, Bar Harbor, ME) with, .AxlKO mice (Dr. Carla Rothlin at Yale University). Genetic have published the research: Axl regulated survival/proliferation network and its therapeutic intervention in mouse models of glomerulonephritis, in the Journal: (JOURNAL)
- what: We showed the therapeutics of Axl inhibition in antiGBM GN.
- future: Encouraging data from this study may facilitate the quick translation of bemcentinib treatment in LN patients either alone or in combination with current standard therapies. Studies are needed to characterize the . . .
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