HIGHLIGHTS
- who: Mari Iida from the Cetuximab (IMC-C225, Erbitux) was purchased from the University of Wisconsin PharmacyGas, and , were obtained from RandD systems (Minneapolis, MN). DMSO (MilliporeSigma, St. Louis, MO) was used as the vehicle control in vitro. Human IgG (MilliporeSigma, St. Louis, MO) was the control for cetuximab. Cell lines and HNSCC PDXs have published the research: AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer, in the Journal: (JOURNAL)
- what: The authors investigate the connection between and_(NRG1) gene expression with a focus on understanding how their interdependent signaling . . .
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