Axl targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model

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  • who: Tony J. Chen from the Female, ­week-­old BALB/c athymic nude mice (Janvier Labs, Le Genest-­Saint-­Isle, France) were used to evaluate the antitumor activity of novel AXL inhibitors in vivoAnimals were housed and maintained in individually ventilated cages under a, %-­60% humidity, ­h light/ dark cycle, at , ±, °C, in SPF conditions at the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University in Krakow, Poland. All experimental procedures were reviewed and approved by the II Regional Ethics Committee on Animal Experimentation, Krakow, Poland (approval no:, ). have published the paper: AXL targeting by . . .

     

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