Azoles as auxiliaries and intermediates in prebiotic nucleoside synthesis

HIGHLIGHTS

  • who: Synthesis et al. from the ugal JRitson, MRC, Laboratory of Molecular Biology, Cambridge , QH, U.K. have published the article: Azoles as Auxiliaries and Intermediates in Prebiotic Nucleoside Synthesis, in the Journal: (JOURNAL) of October/17,/2022
  • what: Our overall scheme for the synthesis of prebiotic nucleosides has now evolved and includes the synthesis of 2-aminothiazole 23 from glycolaldehyde 1, HS-, and NH2CN; the crystallization and separation of glycolaldehyde 1 and glyceraldehyde 3 as their aminals, 1-a and 3-a, respectively; and capture of cyanoacetylene 5 by DCI 18 as the crystalline . . .

     

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