B-1b cells have unique functional traits compared to b-1a cells at homeostasis and in aged hyperlipidemic mice with atherosclerosis

HIGHLIGHTS

  • who: Prasad Srikakulapu from the National Institute on Aging (NIH), United States Johns Hopkins University have published the research work: B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis, in the Journal: (JOURNAL)
  • what: The authors provide evidence that B-1b_cells have greater trafficking to the spleen and IgM production compared to B-1a cells.
  • how: Cell culture data showed that spleen-derived B-1b_cells secrete more total IgM compared to B-1a cells ex vivo providing evidence that B-1b_cells . . .

     

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