B cell-derived anti-beta 2 glycoprotein i antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis

HIGHLIGHTS

• who: Xing Du from the Roche (Basel, Switzerland)Ferrostatin, (Fer-1, ) and liproxstatin, (lip-1, ) were purchased from Selleckchem (Houston, TX, USA). The following antibodies were used in this work. Anti-u03b2 GPI (bs- R) was purchased from Bioss Inc. (Beijing, China). Anti-CBS (cystathionine u03b2-synthase, AP) and anti-CSE (cystathionine u03b3-lyase, AP) were purchased from Proteintech (Rosemont, IL, USA). Anti-, (sc-18916), antinephrin (sc-377246) and anti-PDGFRu03b2 (platelet-derived growth factor receptor beta, sc-374573) were purchased from Santa Cruz Biotech (CA, USA). Anti-4-HNE (4-hydroxynonenal, MAB3249) was purchased from RandD . . .
  

   

  

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