B cell intrinsic and extrinsic factors impacting memory recall responses to srbc challenge

HIGHLIGHTS

  • who: Viviana Valeri from the University at Buffalo, United States have published the Article: B cell intrinsic and extrinsic factors impacting memory recall responses to SRBC challenge, in the Journal: (JOURNAL)
  • how: The authors studied here GC and memory recall responses against SRBC using the AID-Cre-ERT2 fate mapping mouse model. The same observations were made for EYFP+ MBCs and PCs activated in the recall response .

SUMMARY

    A critical help for B cells in GC reactions is provided by T follicular helper (TFH) cells, which recruit B cells into GCs . . .

     

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