B4galnt2-mediated host glycosylation influences the susceptibility to citrobacter rodentium infection

HIGHLIGHTS

• who: . and collaborators from the McGill University, Canada have published the Article: B4galnt2-mediated host glycosylation influences the susceptibility to Citrobacter rodentium infection, in the Journal: (JOURNAL)
• what: The authors demonstrate that the absence of B4galnt2 in the mouse intestine contributes to C. rodentium persistence and inflammation. The authors demonstrate that B4galnt2 deficient mice that lack terminal GalNAc but possess more mannosylated glycoproteins are characterized by increased susceptibility to C. rodentium infection, develop stronger intestinal inflammation and show Frontiers in Microbiology frontiersin.org 10.3389/fmicb.2022.980495 the adhesion experiments using organoid-derived monolayers . . .
  

   

  

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