Bach2 in tregs limits the number of adipose tissue regulatory t cells and restrains type 2 immunity to fungal allergens

HIGHLIGHTS

  • who: Amanda Contreras and colleagues from the Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI, USA have published the research work: BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal Allergens, in the Journal: Journal of Immunology Research 1.2 × 107 of 21/06/2022
  • what: The authors report that ablation of Bach2 in peripheral Tregs leads to enhanced differentiation of effector/tissue Tregs in the lymphoid tissues, increased numbers of visceral adipose_tissue (VAT) Tregs, and increased activation of T_cells in response to . . .

     

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