Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis

HIGHLIGHTS

• who: Bacterial Porin Disrupts Mitochondrial and colleagues from the Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany, Biocenter, Chair of Microbiology, University of Würzburg, Würzburg have published the article: Bacterial Porin Disrupts Mitochondrial Membrane Potential and Sensitizes Host Cells to Apoptosis, in the Journal: (JOURNAL) of October/23,/2009
• what: The authors show that PorB induces the condensation of the matrix and the loss of cristae structures sensitizing cells to the induction of apoptosis via signaling pathways activated by BH3-only proteins. The authors show that PorB enters mitochondria . . .
  

   

  

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