Bacteroides fragilis outer membrane vesicles preferentially activate innate immune receptors compared to their parent bacteria

HIGHLIGHTS

  • who: William J. Gilmore from the Tufts University, United States have published the research work: Bacteroides fragilis outer membrane vesicles preferentially activate innate immune receptors compared to their parent bacteria, in the Journal: (JOURNAL)
  • what: The authors examined the immunogenic cargo associated with B. fragilis OMVs and investigated their ability to enter host epithelial_cells and activate PRRs. The authors show the ability of enriched B. fragilis OMVassociated cargo to be delivered intracellularly to host cells, which ultimately enables B. fragilis OMVs to preferentially activate a broader range of innate immune receptors compared to their parent . . .

     

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