Bacteroides fragilis zy-312 facilitates colonic mucosa regeneration in colitis via motivating stat3 signaling pathway induced by il-22 from ilc3 secretion

HIGHLIGHTS

  • who: April and collaborators from the Delta University for Science and Tsinghua University, China have published the article: Bacteroides fragilis ZY-312 facilitates colonic mucosa regeneration in colitis via motivating STAT3 signaling pathway induced by IL-22 from ILC3 secretion, in the Journal: (JOURNAL)
  • what: Next, the authors aimed to clarify whether the vitality of IL-22-secreting ILC3 was impaired under B. fragilis administration in Stat3u25b3IEC mice.
  • how: The results showed that B. fragilis motivated STAT3 phosphorylation in colonic mucosa with the upregulation of proliferation index Ki-67 and mucus density the . . .

     

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