Bag1: the guardian of anti-apoptotic proteins in acute myeloid leukemia

HIGHLIGHTS

  • who: Myeloid Leukemia and colleagues from the Hematology-Oncology Laboratory, Pediatrics Department, University of Padova, Padova, Italy have published the research: BAG1: The Guardian of Anti-Apoptotic Proteins in Acute Myeloid Leukemia, in the Journal: (JOURNAL) of October/10,/2011
  • what: The authors propose that targeting BAG1 or BAG3 or other specific ubiquitinregulators, such as USP9X, may emerge as a novel therapeutic approach to inhibit AML by reducing elevated apoptotic threshold.
  • how: The experimental results were analyzed by a Cytomics FC500 (Beckman Coulter Brea CA) for a minimum of 10000 events.
 

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