Bag2 interferes with chip-mediated ubiquitination of hsp72

HIGHLIGHTS

  • who: Bianca Schönbühler and colleagues from the Institute of Pathobiochemistry, University Medical Center of the Johannes Gutenberg University, Mainz, address: Department of Biology, University of Konstanz, Konstanz, Germany have published the research: BAG2 Interferes with CHIP-Mediated Ubiquitination of HSP72, in the Journal: (JOURNAL)
  • what: The authors investigated the correlation of BAG2, HSP72, and CHIP and show that BAG2 is a potent inhibitor of the CHIP-mediated ubiquitination of HSP72 in young as well as aged primary human fibroblasts. The authors show that BAG2 protein levels are up-regulated 3 of 10 in . . .

     

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