Baicalein attenuates brain iron accumulation through protecting aconitase 1 from oxidative stress in rotenone-induced parkinson’s disease in rats

HIGHLIGHTS

  • who: Run-Zhe Liu and collaborators from the State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Beijing, China have published the research work: Baicalein Attenuates Brain Iron Accumulation through Protecting Aconitase 1 from Oxidative Stress in Rotenone-Induced Parkinsonu2019s Disease in Rats, in the Journal: Antioxidants 2023, 12, 12. of /2023/
  • what: The authors report that deferiprone could not inhibit IRP1 activation.

SUMMARY

    Deferiprone is an iron chelator that removes excess iron from cells, improves dyskinesia, and attenuates iron accumulation in patients with PD. Hydrogen peroxide or nitric . . .

     

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