Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase*

HIGHLIGHTS

• who: René Jørgensen from the (UNIVERSITY) have published the research: Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase*, in the Journal: (JOURNAL) of March/20,/2013
• what: The authors report four new structures of AAGlyB in complex with, respectively, compound 1 and the HAA substrate ␣-L-Fucp-(132)-␤-D-Galp, compound 2, 2 and HAA, and, finally, UDP and HAA. The authors report herein important new structural and enzymological information on the blood group glycosyltransferase AAGlyB, an enzyme with many characteristic features for the glycosyltransferase family in general.
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