Based on network pharmacology and gut microbiota analysis to investigate the mechanism of the laxative effect of pterostilbene on loperamide-induced slow transit constipation in mice

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  • who: Zhiwei Yao et al. from the Department of Pediatric Surgery, Tianjin Medical University General Hospital, Tianjin, China have published the research: Based on Network Pharmacology and Gut Microbiota Analysis to Investigate the Mechanism of the Laxative Effect of Pterostilbene on Loperamide-Induced Slow Transit Constipation in Mice, in the Journal: (JOURNAL)
  • what: The aim of this study was to verify the laxative effect of PTE in loperamide (LOP)-induced STC model mice and whether these therapeutic effects might be mediated by improving oxidative stress, apoptosis of ICCs and intestinal flora. The study demonstrated that . . .

     

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