Baseline characteristics of patients enrolled in clinical trials of biologics for severe asthma as potential predictors of outcomes

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  • who: Francesco Menzella from the (UNIVERSITY) have published the article: Baseline Characteristics of Patients Enrolled in Clinical Trials of Biologics for Severe Asthma as Potential Predictors of Outcomes, in the Journal: (JOURNAL)
  • what: This study showed a close relationship between baseline BEC and the clinical efficacy of mepolizumab, with efficacy increasing progressively with increasing BEC. In this trial, transient eosinophilia was reported in approximately 14% of patients on active therapy, with normalisation occurring by the end of the treatment period and no patients experiencing clinically relevant adverse events . In all the investigations, respiratory function was . . .

     

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