HIGHLIGHTS
- who: Sang-Heon Park from the (UNIVERSITY) have published the Article: BATF regulates collagen-induced arthritis by regulating T helper cell differentiation, in the Journal: (JOURNAL)
- what: The authors examined whether BATF is required for collagen-induced arthritis (CIA), which is a commonly used experimental model of inflammatory arthritis caused by a T_cell-dependent, antibody-mediated autoimmune_response directed against cartilage type II collagen . The authors show that genetic ablation of Batf in mice suppresses the manifestations of CIA, including synovitis, synovial hyperplasia, angiogenesis in the inflamed synovium, and cartilage/bone erosion in the joint tissues . . .
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