HIGHLIGHTS
- who: Hussein Hamade et al. from the University College Cork, Ireland Sinai, United States have published the article: BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis, in the Journal: (JOURNAL)
- what: The authors investigated the role of BATF3 in maintaining intestinal barrier and development of metabolic syndrome. The authors demonstrate that BATF3-deficiency leads to the development of metabolic syndrome as characterized by insulin resistance, blood glucose and serum insulin levels, increased body weight and white adipocyte size, and development of hepatosteatosis. The authors show that Batf3-/- mice display microbial dysbiosis characterized by . . .
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