Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis

HIGHLIGHTS

  • who: Ben Lambert from the Department of Zoology, University of Oxford, Oxford, UK have published the research: Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis, in the Journal: (JOURNAL)
  • what: Through comparison with experimental data the authors show that growth factor-regulated growth mechanisms can explain early epithelial cell branching but only if epithelial cell division depends in a switch-like way on the local growth factor concentration; cell division occurring only if the driving growth factor level exceeds a threshold. As the roles of GDNF and other growth factors . . .

     

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