Bbppredict: a web service for identifying blood-brain barrier penetrating peptides

HIGHLIGHTS

SUMMARY

    The authors selected five feature encoding methods, including amino_acid composition (AAC), dipeptide composition (DPC), composition of k-spaced amino_acid group pairs (CKSAAGP, k=3), pseudo-amino_acid composition (PAAC) and grouped amino_acid composition (GAAC) to extract the characteristics of peptide sequence. The authors set the length of a peptide to be N, and all feature extraction methods are based on 20 natural amino_acids The authors selected experimentally validated BBPs as candidate positive samples that were collected from Brainpeps (Van Dorpe et_al, 2012), B3Pdb(Kumar et_al, 2021b), public datasets of BBPpred (Dai et_al, 2021) and B3Pred . . .

     

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