Bc2l-c n-terminal lectin domain complexed with histo blood group oligosaccharides provides new structural information

HIGHLIGHTS

  • who: Rafael Bermeo et al. from the (UNIVERSITY) have published the paper: BC2L-C N-Terminal Lectin Domain Complexed with Histo Blood Group Oligosaccharides Provides New Structural Information, in the Journal: (JOURNAL)
  • what: The authors report here the production of a novel recombinant form of BC2L-CN (rBC2L-CN2) which allowed better protein stability and unprecedented co-crystallization with oligosaccharides.
  • how: The authors designed a novel construct for BC2L-CN to allow crystallographic studies with oligosaccharides
  • future: Since both BC2L-C domains have millimolar affinity for l-fucose (personal communication of . . .

     

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