Bcg therapy downregulates hla-i on malignant cells to subvert antitumor immune responses in bladder cancer

HIGHLIGHTS

• who: Mathieu Rouanne et al. from the Department Columbia University Paris-Saclay, Villejuif, France The CRUK have published the article: BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer, in the Journal: (JOURNAL) of June/15,/2022
• what: Using cancer cell lines freshly resected human bladder tumors and samples from cohorts of patients with bladder cancer before and after BCG therapy the authors demonstrate 2 distinct patterns of immune subversion upon BCG relapse. The authors investigated the effects of BCG immunotherapy on the biology of bladder cancers. Although . . .
  

   

  

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