Bci, an inhibitor of the dusp1 and dusp6 dual speci city phosphatases, enhances p2x7 receptor expression in neuroblastoma cells

HIGHLIGHTS

• who: BCI et al. from the University Ferrara, Italy have published the Article: BCI, an inhibitor of the DUSP1 and DUSP6 dual speci city phosphatases, enhances P2X7 receptor expression in neuroblastoma cells, in the Journal: (JOURNAL)
• what: The authors show that BCI-dependent inhibition of DUSPs produces a potent upregulation of P2RX7 in neuroblastoma cells and that this effect is partially mediated by p38 activation.
• how: The commercial antibodies used in the study were raised against P2RX7 (PR-004 Alomone Laboratories) Sp1 (#07-645 Merck Millipore) SAPK/JNK (#9252) anti-phospho-SAPK/JNK . . .
  

   

  

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