Bcl-xl is a key mediator of apoptosis following kras inhibition in kras mutant colorectal cancer. hajrah khawaja , rebecca briggs , cheryl h. latimer , mustasin rassel , daryl griffin ,

HIGHLIGHTS

• who: Kingdom. and colleagues from the Cancer Research, Queenu2019s University Belfast, Lisburn Road, Belfast , AE, UnitedBelfast, AE, United Kingdom have published the research work: Bcl-xL is a key mediator of apoptosis following KRAS inhibition in KRAS mutant colorectal cancer. Hajrah Khawaja , Rebecca Briggs , Cheryl H. Latimer , Mustasin Rassel , Daryl Griffin ,, in the Journal: (JOURNAL) of 16/05/2023
• what: The authors characterize the activity of AZ`1569 , a novel KRASG12C inhibitor, in a panel of KRASG12CMT CRC cells. Using genomic and proteomic analyses, the authors show that AZ`1569-acquired resistant models have high . . .
  

   

  

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