Bcorl1 s878g, gnb1 g116s, sh2b3 a536t, and kmt2d s3708r tetramutation co-contribute to a pediatric acute myeloid leukemia: case report and literature review

HIGHLIGHTS

  • who: Liang Wang et al. from the (UNIVERSITY) have published the article: BCORL1 S878G, GNB1 G116S, SH2B3 A536T, and KMT2D S3708R tetramutation co-contribute to a pediatric acute myeloid leukemia: Case report and literature review, in the Journal: (JOURNAL)
  • future: Due to the low number of co-mutations in BCORL1-mutated AML additional studies are necessary to confirm prognostic information.

SUMMARY

    Acute myeloid leukemia (AML) is a complex and dynamic disease characterized by high molecular heterogeneity, representing 15%-20% of leukemias in children. Sequence variants were categorized into four categories based . . .

     

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