Bdnf augmentation using riluzole reverses doxorubicin-induced decline in cognitive function and neurogenesis

HIGHLIGHTS

  • who: Manal T. Usmani from the Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, CA, USA have published the research work: BDNF Augmentation Using Riluzole Reverses Doxorubicin-Induced Decline in Cognitive Function and Neurogenesis, in the Journal: (JOURNAL)
  • what: This study provided pre-clinical evidence that RZ reverses chemotherapy-induced cognitive decline in a mouse model.
  • how: For this pre-clinical study the authors used adult female mice. The statistical analyses of cognitive function biochemical and immunohistochemical data were conducted using a two-way ANOVA (GraphPad Prism v8.0 . . .

     

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