HIGHLIGHTS
- who: Tanya Gandhi from the University of Florida, United States have published the paper: Behavioral regulation by perineuronal nets in the prefrontal cortex of the CNTNAP2 mouse model of autism spectrum disorder, in the Journal: (JOURNAL)
- what: The authors assessed whether alterations in PNNs and PV-positive cells in the prefrontal cortex (PFC) of CNTNAP2-/- mice could underlie autistic-like behaviors in adult mice.
- how: Offspring of the breeders were used in the study.
- future: Future studies targeting specific removal of PNN components are required to understand individual component effect on . . .
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