Berberine increases stromal production of wnt molecules and activates lgr5

HIGHLIGHTS

• who: Zecheng Luo from the All mouse works followed the recommendations of the National Research Council Guide for the Care and Use of Laboratory Animals, with the protocols approved by the Institutional Animal Care and Use Committee of Shanghai, China [SYXK(SH)2011-0112]Male C BL/, mice, age, ~, weeks, weight, ~25g, were obtained from the Shanghai Model Organisms Center, Inc. Lgr5-GFPCreERT mice were generated in Hans Clever`s lab and Rosa-tdTomato mice were purchased from The Jackson Laboratories. The mice were maintained in the SPF animal facility of Shanghai Jiao Tong University. The colon . . .
  

   

  

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