HIGHLIGHTS
- who: Benas Balandis and collaborators from the Department of Organic Chemistry, Kaunas University of Technology, Radvileu0307nuu02db pl, have published the article: Beta and Gamma Amino Acid-Substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases, in the Journal: Pharmaceuticals 2022, 15, 477. of /2022/
- what: The analysis showed that the chlorine atom in the meta-position of para-N u03b2-amino_acid bearing benzenesulfonamide derivatives increases the observed affinity for CA over non-chlorinated compounds, while the substituents located further away from this group of benzenesulfonamides have lower influence on the affinity.
- how: Pyrrolidinones 1ab . . .
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