HIGHLIGHTS
- who: Teresa Rossi from the (UNIVERSITY) have published the research: BETi enhance ATGL expression and its lipase activity to exert their antitumoral effects in triple-negative breast cancer (TNBC) cells, in the Journal: (JOURNAL)
- what: Methods MDA-MB231 cells treated with JQ1 followed by RNA-sequencing analysis showed altered of metabolic genes; among these the authors focused on a lipase required for efficient mobilization of triglyceride. This study showed that altered the mitochondrial dynamics taking advantage of function to induce cell cycle arrest and cell death. The authors aim to evaluate if BETi can rewire . . .
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