Beyond the foam cell: the role of lxrs in preventing atherogenesis

HIGHLIGHTS

• who: Adil Rasheed and Carolyn L. Cummins from the Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON M S , Canada have published the research: Beyond the Foam Cell: The Role of LXRs in Preventing Atherogenesis, in the Journal: (JOURNAL)
• what: LXRs regulate atherosclerotic development LXR activation promotes plaque regression ↑ aortic root lesion area of Lxrα-/- Apoe-/- compared to Apoe-/- GW ↓ aortic root lesion area in Apoe-/- and Lxrα-/- Apoe-/- ↑ aortic root lesion area in Lxrα-/- Ldlr-/- vs. Ldlr-/- T09: ↓ aortic root lesion area in Ldlr-/-, Lxrα-/- Ldlr-/-, and Lxrβ-/- Ldlr-/- Basal LXRβ does not . . .
  

   

  

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