Biased gpcr signaling by the native parathyroid hormone-related protein 1 to 141 relative to its n-terminal fragment 1 to

HIGHLIGHTS

• who: Karina A. Peu00f1a from the (UNIVERSITY) have published the research work: Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its N-terminal fragment 1 to, in the Journal: (JOURNAL) of January/11,/2022
• what: The authors demonstrate using various fluorescence imaging approaches at the single cell level to measure kinetics of_(i) receptor activation, (ii) receptor signaling via Gs and Gq, and_(iii) receptor internalization and recycling that the native PTHrP1-141 displays biased agonist signaling properties that are not mimicked by PTHrP1-36. The authors show . . .
  

   

  

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