Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the c-terminal phenylalanine*

HIGHLIGHTS

• who: Emilie Ceraudo from the (UNIVERSITY) have published the Article: Biased Signaling Favoring Gi over β-Arrestin Promoted by an Apelin Fragment Lacking the C-terminal Phenylalanine*, in the Journal: (JOURNAL) of August/29,/2014
• what: The authors show that the C-terminal Phe of apelin plays a critical role in ␤-arrestin recruitment to the ApelinR but is not involved in G␣i protein activation nor adenylyl cyclase inhibition.
• how: The plates were then read in a Mithras LB940 instrument (Berthold Technologies Bad Wildbad Germany) and data were collected using the MicroWin 2000 software . . .
  

   

  

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