Big-slice: a highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters

HIGHLIGHTS

  • who: GigaScience et al. from the Wageningen University, Droevendaalsesteeg, PB, Wageningen, The Netherlands have published the paper: BiG-SLiCE: A highly scalable tool maps the diversity of 1.2 million biosynthetic gene clusters, in the Journal: (JOURNAL) of 26/08/2020
  • what: The authors demonstrate the utility of such analyses by reconstructing a global map of secondary metabolic diversity across taxonomy to identify uncharted biosynthetic potential. Using this ranked normalization scoring strategy for building the numerical feature representation of each core gene, the authors show that the sub-Pfams can together act as a proxy . . .

     

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