Bilayer membrane modulation of membrane type 1 matrix metalloproteinase (mt1-mmp) structure and proteolytic activity

HIGHLIGHTS

  • who: Bilayer Membrane Modulation et al. from the Atlantic University, Parkside Drive, Jupiter, FL, USA have published the paper: Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity, in the Journal: Scientific Reports Scientific Reports
  • what: This study has indicated the same overall interaction region within the HPX domain, and specifically R330 and R345 (Figs 3C and S5).

SUMMARY

    The X-ray crystallographic structure of the MT1-MMP CAT domain, in complex with tissue inhibitor of metalloproteinases (TIMPs), has been reported (pdb 3MA2, 1BUV, 1BQQ . . .

     

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