Binding modes of two scorpion toxins to the voltage-gated potassium channel kv1.3 revealed from molecular dynamics

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  • who: Rong Chen and Shin-Ho Chung from the Research School of Biology, Australian National University, Canberra, ACT, Australia have published the article: Binding Modes of Two Scorpion Toxins to the Voltage-Gated Potassium Channel Kv1.3 Revealed from Molecular Dynamics, in the Journal: Toxins 2014, 6, 2149-2161 of 30/05/2014
  • what: The authors show that Lys28 of MgTx, which is believed to be the residue physically occluding the filter of Kv1.3, is unable to form stable interactions with the channel pore. The authors show that Arg24 of HgTx is able to . . .

     

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