HIGHLIGHTS
- who: Omar Rawashdeh from the (UNIVERSITY) have published the research work: Bio-informatic analysis of CRISPR protospacer adjacent motifs (PAMs) in T4 genome, in the Journal: (JOURNAL)
- what: The authors did investigate some of the possible reasons for CRISPR selection of PAM sequences, specifically, the gene essentiality and function, surface exposure of amino_acids, and whether the conservation of regulatory_sequences in T4 Phages promoters raises their chance of being chosen as PAMs in CRISPR-Cas. This work provides the first examination, to the knowledge , of the coordinates and localization of PAMs motifs in phage genomes.
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