HIGHLIGHTS
- who: BMC Biotechnology et al. from the Academic Medical Center of the University of Amsterdam, Meibergdreef, AZ Amsterdam, The Netherlands and Lehrstuhl fur have published the paper: Bio Med Central, in the Journal: (JOURNAL)
- what: We generated a novel sc-rtTA variant that is more active and more dox-sensitive than the original sc-rtTA, and does not show any background activity in the absence of dox.
- how: This variant was also less sensitive to interference by coexpressed TetR-based tTS repressor protein and may therefore be more suitable for applications where multiple . . .
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