HIGHLIGHTS
- who: BMC Genomics and collaborators from the GP23/A, Italy and Biology Department, Area, University have published the Article: Bio Med Central, in the Journal: (JOURNAL)
- what: Based on a multiple sequence alignment, the authors propose a modified signature for the CDF family that takes account of newly characterised members. The authors identified residues that are crucial for function in the model eukaryotic Zn-CDF PtdMTP1.
SUMMARY
Key functional amino_acid residues, identified by site-directed_mutagenesis, reside in the three amphipathic and conserved transmembrane helices II, V and VI, which are supposed . . .
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