Biochemical analysis of point mutations in the 5⠲-3⠲ exonuclease of dna polymerase i of streptococcus pneumoniae

HIGHLIGHTS

• who: Mo̕nica Amblar from the (UNIVERSITY) have published the research work: Biochemical Analysis of Point Mutations in the 5⠲-3⠲ Exonuclease of DNA Polymerase I of Streptococcus pneumoniae, in the Journal: (JOURNAL) of September/22,/2000
• what: Quantification of the experiments, shown in Fig 3, allowed the authors to categorize the mutant proteins in terms of their exonuclease activity .

SUMMARY

The mutations, but not the fusion to the C-terminal end of the wild-type, reduced the exonuclease activity. Some clues to identify important residues in the bacterial 5⬘-3 . . .

 



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