Biochemical characterization of recombinant influenza a polymerase heterotrimer complex: endonuclease activity and evaluation of inhibitors

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  • who: Weimei Xing and colleagues from the Editor: Mirco Schmolke, University of Geneva have published the paper: Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0181969]. August 15, 2017 of March/20,/2017
  • what: The authors characterized the endonuclease activity of recombinant proteins of influenza A/PR8 containing full length PA PA/PB1 dimer and PA/PB1/PB2 trimer observing 8.3- 265- and 142-fold higher activity than PAN respectively. The study demonstrates that the . . .

     

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