Biochemical characterization of the atpase and helicase activity of uap56, an essential pre-mrna splicing and mrna export factor*

HIGHLIGHTS

• who: Jingping Shen from the Jingping Shen, Lingdi Zhang, and Rui Zhao, From the Department of Biochemistry and Molecular Genetics, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado , DEXD/H-box protein , is an essential pre-mRNA splicing factor required for the first ATP-dependent spliceosome assembly step, is also essential for the export of the majority of mRNAs from the nucleus to the cytoplasm. We performed biochemical characterization of UAP56's ATPase and helicase activity, which is important for further understanding the role of these activities in UAP56's function. We showed that . . .
  

   

  

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