Bioconjugation strategies for connecting proteins to dna-linkers for single-molecule force-based experiments

HIGHLIGHTS

  • who: Lyan M. van der Sleen and Katarzyna M. Tych from the Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen have published the paper: Bioconjugation Strategies for Connecting Proteins to DNA-Linkers for Single-Molecule Force-Based Experiments, in the Journal: Nanomaterials 2021, 2424 of /2021/

SUMMARY

    Such polymers are commercially available with a variety of terminal functional_groups. The rupture of a covalent_bond can require forces exceeding 2 nN and therefore provides a more stable and stronger link between the POI and DNA than the aforementioned methods. Conjugation strategies requiring only one . . .

     

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