Bioengineered embryoids mimic post-implantation development in vitro

HIGHLIGHTS

  • who: Mehmet U. Girgin from the Institut University of Cambridge, Cambridge, UK have published the article: Bioengineered embryoids mimic post-implantation development in vitro, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The experiments show how bioengineering-inspired approaches can be exploited to standardize complex embryoid models and allow for the modeling of embryonic-extraembryonic cell/ tissue interactions involved in the generation of precise patterns during development.
  • how: These results showed that in EpiTS embryoids both WNT and TGF-β pathways are active and their dynamics depend on the epithelial architecture of the EPI . . .

     

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