Bioengineering the vascularized endocrine pancreas: a fine-tuned interplay between vascularization, extracellular-matrix-based scaffold architecture, and insulin-producing cells

HIGHLIGHTS

  • who: Endocrine Pancreas A Fine-Tuned et al. from the Raffaele, Milan, Italy have published the research: Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells, in the Journal: (JOURNAL)
  • what: This study showed that rat islets, in combination with additional supporting cells, were able to engraft and restore normoglycemia for up to 4 months. The study showed the ability of the chamber to obtain a microvascularized network after 28 days and to sustain the engraftment and function of syngeneic islets after 10-14 . . .

     

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