Bioequivalence of two tablet formulations of cefpodoxime proxetil in beagle dogs

HIGHLIGHTS

  • who: De-Gang Zhou from the Henan University of Science and Technology, China have published the paper: Bioequivalence of two tablet formulations of cefpodoxime proxetil in beagle dogs, in the Journal: (JOURNAL)
  • what: This study aimed to compare the pharmacokinetic profiles of domestically produced cefpodoxime proxetil with SIMPLICEF R (Zoetis) to assess their bioequivalence and, ultimately, the potential for substitution in dogs.
  • how: The reference-scaled average bioequivalence (RSABE) method was used to perform the bioequivalence analysis . Cefpodoxime has been demonstrated to be a highly variable drug which is why a four-way . . .

     

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