Biogenesis of hdl by saa is dependent on abca1 in the liver in vivos↞

HIGHLIGHTS

• who: Hu Wei from the Biochemistry*, City UniversityKochi, Japan have published the paper: Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivos↞, in the Journal: (JOURNAL) of 15/Nov/2007
• how: The data indicated that SAA and apoA-I are both secreted by hepatocytes regardless of ABCA1 genotype although the production of HDL with these proteins requires ABCA1. The authors investigated the mechanism for the biogenesis of SAA-HDL and a role of ABCA1 in a mouse model using ABCA1-KO mice. The results showed that the production and secretion . . .
  

   

  

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