HIGHLIGHTS
- who: ufeffJialiuufeff ufeffJiangufeff and ufeffKarl R.ufeff ufeffSchmitzufeff from the Germany Heidelberg University have published the article: Bioinformatic identification of ClpI, a distinct class of Clp unfoldases in Actinomycetota, in the Journal: (JOURNAL)
- how: The authors compared the state of this linker region in AlphaFold2 models of ClpB ClpC and ClpI (Supplementary Figure S5A).
SUMMARY
ClpB operates as a chaperone and disaggregase, remodeling and releasing client proteins to refold in the cytosol (Weibezahn et_al, 2004; Rosenzweig et_al, 2013; Alam et_al, 2021). ClpC functions as the unfoldase component of the ClpCP1P2 protease . . .
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